The tops of your feet to the toes. It also comes in a gel. Pin On Lower Back Pain Last updated february 9, 2021. Does biofreeze work on nerve pain . Biofreeze works within the body's nervous system to block pain signals at the source, decreasing inflammation at the muscles and joints. Does biofreeze work on nerve pain overview does biofreeze work on nerve pain if you have lost feeling in your extremities, you may be suffering from peripheral neuropathy. Biofreeze can be used throughout the day and offers no adverse effects. There are two types of fibers, heat sensing and cold sensing. Biofreeze is #1 clinically used and recommended topical analgesic that has been providing relief to countless arthritis sufferers. I know someone who uses it for shingles pain instead of the lido patches. About biofreeze biofreeze® is the #1 used and recommended topical pain. I typically recommend the spray form, likening it to a fire extinguisher to spray away the burning. To un...